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Regnase-1 in microglia negatively regulates high mobility group box 1-mediated inflammation and neuronal injury
Extracellular high mobility group box 1 (HMGB1) has been demonstrated to function as a proinflammatory cytokine and induces neuronal injury in response to various pathological stimuli in central nervous system (CNS). However, the regulatory factor involved in HMGB1-mediated inflammatory signaling is...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820713/ https://www.ncbi.nlm.nih.gov/pubmed/27044405 http://dx.doi.org/10.1038/srep24073 |