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Structural basis for the membrane association of ankyrinG via palmitoylation

By clustering various ion channels and transporters, ankyrin-G (AnkG) configures the membrane-excitation platforms in neurons and cardiomyocytes. AnkG itself localizes to specific areas on the plasma membrane via s-palmitoylation of Cys. However, the structural mechanism by which AnkG anchors to the...

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Detalles Bibliográficos
Autores principales: Fujiwara, Yuichiro, Kondo, Hiroko X., Shirota, Matsuyuki, Kobayashi, Megumi, Takeshita, Kohei, Nakagawa, Atsushi, Okamura, Yasushi, Kinoshita, Kengo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820748/
https://www.ncbi.nlm.nih.gov/pubmed/27046665
http://dx.doi.org/10.1038/srep23981