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Revealing a new activity of the human Dicer DUF283 domain in vitro

The ribonuclease Dicer is a multidomain enzyme that plays a fundamental role in the biogenesis of small regulatory RNAs (srRNAs), which control gene expression by targeting complementary transcripts and inducing their cleavage or repressing their translation. Recent studies of Dicer’s domains have p...

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Detalles Bibliográficos
Autores principales: Kurzynska-Kokorniak, Anna, Pokornowska, Maria, Koralewska, Natalia, Hoffmann, Weronika, Bienkowska-Szewczyk, Krystyna, Figlerowicz, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820750/
https://www.ncbi.nlm.nih.gov/pubmed/27045313
http://dx.doi.org/10.1038/srep23989