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Combined approaches of EPR and NMR illustrate only one transmembrane helix in the human IFITM3

Interferon-inducible transmembrane protein IFITM3 was known to restrict the entry of a wide spectrum of viruses to the cytosol of the host. The mechanism used by the protein to restrict viral entry is unclear given the unavailability of the membrane topology and structures of the IFITM family protei...

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Detalles Bibliográficos
Autores principales: Ling, Shenglong, Zhang, Chengwei, Wang, Wei, Cai, Xiaoying, Yu, Lu, Wu, Fangming, Zhang, Longhua, Tian, Changlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820770/
https://www.ncbi.nlm.nih.gov/pubmed/27046158
http://dx.doi.org/10.1038/srep24029