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Combined approaches of EPR and NMR illustrate only one transmembrane helix in the human IFITM3
Interferon-inducible transmembrane protein IFITM3 was known to restrict the entry of a wide spectrum of viruses to the cytosol of the host. The mechanism used by the protein to restrict viral entry is unclear given the unavailability of the membrane topology and structures of the IFITM family protei...
Autores principales: | Ling, Shenglong, Zhang, Chengwei, Wang, Wei, Cai, Xiaoying, Yu, Lu, Wu, Fangming, Zhang, Longhua, Tian, Changlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820770/ https://www.ncbi.nlm.nih.gov/pubmed/27046158 http://dx.doi.org/10.1038/srep24029 |
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