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Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation

It is increasingly recognized that molecular chaperones play a key role in modulating the formation of amyloid fibrils, a process associated with a wide range of human disorders. Understanding the detailed mechanisms by which they perform this function, however, has been challenging because of the g...

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Detalles Bibliográficos
Autores principales: Arosio, Paolo, Michaels, Thomas C. T., Linse, Sara, Månsson, Cecilia, Emanuelsson, Cecilia, Presto, Jenny, Johansson, Jan, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820785/
https://www.ncbi.nlm.nih.gov/pubmed/27009901
http://dx.doi.org/10.1038/ncomms10948