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Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
It is increasingly recognized that molecular chaperones play a key role in modulating the formation of amyloid fibrils, a process associated with a wide range of human disorders. Understanding the detailed mechanisms by which they perform this function, however, has been challenging because of the g...
Autores principales: | Arosio, Paolo, Michaels, Thomas C. T., Linse, Sara, Månsson, Cecilia, Emanuelsson, Cecilia, Presto, Jenny, Johansson, Jan, Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820785/ https://www.ncbi.nlm.nih.gov/pubmed/27009901 http://dx.doi.org/10.1038/ncomms10948 |
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