Specific interference shRNA-expressing plasmids inhibit Hantaan virus infection in vitro and in vivo

AIM: To investigate the antiviral effects of vectors expressing specific short hairpin RNAs (shRNAs) against Hantaan virus (HTNV) infection in vitro and in vivo. METHODS: Based on the effects of 4 shRNAs targeting different regions of HTNV genomic RNA on viral replication, the most effective RNA int...

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Detalles Bibliográficos
Autores principales: Liu, Yuan-yuan, Chen, Liang-jun, Zhong, Yan, Shen, Meng-xin, Ma, Nian, Liu, Bing-yu, Luo, Fan, Hou, Wei, Yang, Zhan-qiu, Xiong, Hai-rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820803/
https://www.ncbi.nlm.nih.gov/pubmed/26972493
http://dx.doi.org/10.1038/aps.2015.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820803/
https://www.ncbi.nlm.nih.gov/pubmed/26972493
http://dx.doi.org/10.1038/aps.2015.165

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