FoxO1-mediated autophagy is required for NK cell development and innate immunity

Natural killer (NK) cells exert a crucial role in early immune responses as a major innate effector component. However, the underlying mechanisms of NK cell development remain largely elusive. Here we show that robust autophagy appears in the stage of immature NK cells (iNKs), which is required for...

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Detalles Bibliográficos
Autores principales: Wang, Shuo, Xia, Pengyan, Huang, Guanling, Zhu, Pingping, Liu, Jing, Ye, Buqing, Du, Ying, Fan, Zusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820827/
https://www.ncbi.nlm.nih.gov/pubmed/27010363
http://dx.doi.org/10.1038/ncomms11023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820827/
https://www.ncbi.nlm.nih.gov/pubmed/27010363
http://dx.doi.org/10.1038/ncomms11023

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