Cargando…

Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness

Oligomerization of transcription factors controls their translocation into the nucleus and DNA-binding activity. Here we present a fluorescence microscopy analysis termed pCOMB (pair correlation of molecular brightness) that tracks the mobility of different oligomeric species within live cell nuclea...

Descripción completa

Detalles Bibliográficos
Autores principales: Hinde, Elizabeth, Pandžić, Elvis, Yang, Zhengmin, Ng, Ivan H. W., Jans, David A., Bogoyevitch, Marie A., Gratton, Enrico, Gaus, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820838/
https://www.ncbi.nlm.nih.gov/pubmed/27009358
http://dx.doi.org/10.1038/ncomms11047