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Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
Oligomerization of transcription factors controls their translocation into the nucleus and DNA-binding activity. Here we present a fluorescence microscopy analysis termed pCOMB (pair correlation of molecular brightness) that tracks the mobility of different oligomeric species within live cell nuclea...
Autores principales: | Hinde, Elizabeth, Pandžić, Elvis, Yang, Zhengmin, Ng, Ivan H. W., Jans, David A., Bogoyevitch, Marie A., Gratton, Enrico, Gaus, Katharina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820838/ https://www.ncbi.nlm.nih.gov/pubmed/27009358 http://dx.doi.org/10.1038/ncomms11047 |
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