Neuronal activity controls Bdnf expression via Polycomb de-repression and CREB/CBP/JMJD3 activation in mature neurons

It has been recently described that in embryonic stem cells, the expression of some important developmentally regulated genes is repressed, but poised for fast activation under the appropriate stimuli. In this work we show that Bdnf promoters are repressed by Polycomb Complex 2 in mature hippocampal...

Descripción completa

Detalles Bibliográficos
Autores principales: Palomer, Ernest, Carretero, Javier, Benvegnù, Stefano, Dotti, Carlos G., Martin, Mauricio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820842/
https://www.ncbi.nlm.nih.gov/pubmed/27010597
http://dx.doi.org/10.1038/ncomms11081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820842/
https://www.ncbi.nlm.nih.gov/pubmed/27010597
http://dx.doi.org/10.1038/ncomms11081

Ejemplares similares