Bidirectional regulation of synaptic transmission by BRAG1/IQSEC2 and its requirement in long-term depression

Dysfunction of the proteins regulating synaptic function can cause synaptic plasticity imbalance that underlies neurological disorders such as intellectual disability. A study found that four distinct mutations within BRAG1, an Arf-GEF synaptic protein, each led to X-chromosome-linked intellectual d...

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Detalles Bibliográficos
Autores principales: Brown, Joshua C., Petersen, Amber, Zhong, Ling, Himelright, Miranda L., Murphy, Jessica A., Walikonis, Randall S., Gerges, Nashaat Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820844/
https://www.ncbi.nlm.nih.gov/pubmed/27009485
http://dx.doi.org/10.1038/ncomms11080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820844/
https://www.ncbi.nlm.nih.gov/pubmed/27009485
http://dx.doi.org/10.1038/ncomms11080

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