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Bidirectional regulation of synaptic transmission by BRAG1/IQSEC2 and its requirement in long-term depression
Dysfunction of the proteins regulating synaptic function can cause synaptic plasticity imbalance that underlies neurological disorders such as intellectual disability. A study found that four distinct mutations within BRAG1, an Arf-GEF synaptic protein, each led to X-chromosome-linked intellectual d...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820844/ https://www.ncbi.nlm.nih.gov/pubmed/27009485 http://dx.doi.org/10.1038/ncomms11080 |