Genome scale patterns of supercoiling in a bacterial chromosome

DNA in bacterial cells primarily exists in a negatively supercoiled state. The extent of supercoiling differs between regions of the chromosome, changes in response to external conditions and regulates gene expression. Here we report the use of trimethylpsoralen intercalation to map the extent of su...

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Detalles Bibliográficos
Autores principales: Lal, Avantika, Dhar, Amlanjyoti, Trostel, Andrei, Kouzine, Fedor, Seshasayee, Aswin S. N., Adhya, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820846/
https://www.ncbi.nlm.nih.gov/pubmed/27025941
http://dx.doi.org/10.1038/ncomms11055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820846/
https://www.ncbi.nlm.nih.gov/pubmed/27025941
http://dx.doi.org/10.1038/ncomms11055

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