Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads

BACKGROUND: Gene isoforms are commonly found in both prokaryotes and eukaryotes. Since each isoform may perform a specific function in response to changing environmental conditions, studying the dynamics of gene isoforms is important in understanding biological processes and disease conditions. Howe...

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Detalles Bibliográficos
Autores principales: Liang, Ma, Raley, Castle, Zheng, Xin, Kutty, Geetha, Gogineni, Emile, Sherman, Brad T., Sun, Qiang, Chen, Xiongfong, Skelly, Thomas, Jones, Kristine, Stephens, Robert, Zhou, Bin, Lau, William, Johnson, Calvin, Imamichi, Tomozumi, Jiang, Minkang, Dewar, Robin, Lempicki, Richard A., Tran, Bao, Kovacs, Joseph A., Huang, Da Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820869/
https://www.ncbi.nlm.nih.gov/pubmed/27051465
http://dx.doi.org/10.1186/s13040-016-0090-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820869/
https://www.ncbi.nlm.nih.gov/pubmed/27051465
http://dx.doi.org/10.1186/s13040-016-0090-8

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