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Force degradation behavior of glucocorticoid deflazacort by UPLC: isolation, identification and characterization of degradant by FTIR, NMR and mass analysis

In this investigation, sensitive and reproducible methods are described for quantitative determination of deflazacort in the presence of its degradation product. The method was based on high performance liquid chromatography of the drug from its degradation product on reverse phase using Acquity UPL...

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Detalles Bibliográficos
Autores principales: Deshmukh, Rajesh, Sharma, Lata, Tekade, Muktika, Kesharwani, Prashant, Trivedi, Piyush, Tekade, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820892/
https://www.ncbi.nlm.nih.gov/pubmed/28276670
http://dx.doi.org/10.7555/JBR.30.20150074