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Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner

BACKGROUND: Males and females have a different predisposition for the development of intestinal disorders, like inflammatory bowel disease (IBD). We hypothesized that sex specific differences in intestinal immune responses may underlie this bias. To test this hypothesis, we studied sex differences i...

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Detalles Bibliográficos
Autores principales: Elderman, Marlies, van Beek, Adriaan, Brandsma, Eelke, de Haan, Bart, Savelkoul, Huub, de Vos, Paul, Faas, Marijke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820953/
https://www.ncbi.nlm.nih.gov/pubmed/27051505
http://dx.doi.org/10.1186/s13293-016-0075-9