A Molecular Chipper technology for CRISPR sgRNA library generation and functional mapping of noncoding regions

Clustered regularly-interspaced palindromic repeats (CRISPR)-based genetic screens using single-guide-RNA (sgRNA) libraries have proven powerful to identify genetic regulators. Applying CRISPR screens to interrogate functional elements in noncoding regions requires generating sgRNA libraries that ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Jijun, Roden, Christine A., Pan, Wen, Zhu, Shu, Baccei, Anna, Pan, Xinghua, Jiang, Tingting, Kluger, Yuval, Weissman, Sherman M., Guo, Shangqin, Flavell, Richard A., Ding, Ye, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820989/
https://www.ncbi.nlm.nih.gov/pubmed/27025950
http://dx.doi.org/10.1038/ncomms11178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820989/
https://www.ncbi.nlm.nih.gov/pubmed/27025950
http://dx.doi.org/10.1038/ncomms11178

Ejemplares similares