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Digoxin Inhibits Induction of Experimental Autoimmune Uveitis in Mice, but Causes Severe Retinal Degeneration

PURPOSE: Digoxin, a major medication for heart disease, was recently reported to have immunosuppressive capacity. Here, we determined the immunosuppressive capacity of digoxin on the development of experimental autoimmune uveitis (EAU) and on related immune responses. METHODS: The B10.A mice were im...

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Detalles Bibliográficos
Autores principales: Hinshaw, Samuel J. H., Ogbeifun, Osato, Wandu, Wambui S., Lyu, Cancan, Shi, Guangpu, Li, Yichao, Qian, Haohua, Gery, Igal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821074/
https://www.ncbi.nlm.nih.gov/pubmed/27028065
http://dx.doi.org/10.1167/iovs.15-19040