Genetic Association between Presenilin 2 Polymorphisms and Alzheimer's Disease and Dementia of Lewy Body Type in a Japanese Population

BACKGROUND/AIMS: Mutations in the presenilin 2 (PSEN2) gene cause familial Alzheimer's disease (AD). Common polymorphisms affect gene activity and increase the risk of AD. Nonsynonymous polymorphisms in the PSEN2 gene showed Lewy body dementia (LBD) phenotypes clinically. Therefore, we aimed to...

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Detalles Bibliográficos
Autores principales: Suzuki, Ayako, Shibata, Nobuto, Kasanuki, Koji, Nagata, Tomoyuki, Shinagawa, Shunichiro, Kobayashi, Nobuyuki, Ohnuma, Tohru, Takeshita, Yoshihide, Kawai, Eri, Takayama, Toshiki, Nishioka, Kenya, Motoi, Yumiko, Hattori, Nobutaka, Nakayama, Kazuhiko, Yamada, Hisashi, Arai, Heii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821141/
https://www.ncbi.nlm.nih.gov/pubmed/27065294
http://dx.doi.org/10.1159/000444080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821141/
https://www.ncbi.nlm.nih.gov/pubmed/27065294
http://dx.doi.org/10.1159/000444080

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