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TNF-α-induced NF-κB activation upregulates microRNA-150-3p and inhibits osteogenesis of mesenchymal stem cells by targeting β-catenin

Although systemic or local inflammation, commonly featured by cytokine activation, is implicated in patients with bone loss, the underlying mechanisms are still elusive. As microRNAs (miR), a class of small non-coding RNAs involved in essential physiological processes, have been found in bone cells,...

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Detalles Bibliográficos
Autores principales: Wang, Nan, Zhou, Zubin, Wu, Tianyi, Liu, Wei, Yin, Peipei, Pan, Chenhao, Yu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821240/
https://www.ncbi.nlm.nih.gov/pubmed/26935950
http://dx.doi.org/10.1098/rsob.150258