Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification

The interaction of a large number of extracellular proteins with heparan sulfate (HS) regulates their transport and effector functions, but the degree of molecular specificity underlying protein–polysaccharide binding is still debated. The 15 paracrine fibroblast growth factors (FGFs) are one of the...

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Detalles Bibliográficos
Autores principales: Li, Yong, Sun, Changye, Yates, Edwin A., Jiang, Chao, Wilkinson, Mark C., Fernig, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821243/
https://www.ncbi.nlm.nih.gov/pubmed/27030175
http://dx.doi.org/10.1098/rsob.150275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821243/
https://www.ncbi.nlm.nih.gov/pubmed/27030175
http://dx.doi.org/10.1098/rsob.150275

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