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Heparin binding preference and structures in the fibroblast growth factor family parallel their evolutionary diversification
The interaction of a large number of extracellular proteins with heparan sulfate (HS) regulates their transport and effector functions, but the degree of molecular specificity underlying protein–polysaccharide binding is still debated. The 15 paracrine fibroblast growth factors (FGFs) are one of the...
Autores principales: | Li, Yong, Sun, Changye, Yates, Edwin A., Jiang, Chao, Wilkinson, Mark C., Fernig, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821243/ https://www.ncbi.nlm.nih.gov/pubmed/27030175 http://dx.doi.org/10.1098/rsob.150275 |
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