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Selectivity in glycosaminoglycan binding dictates the distribution and diffusion of fibroblast growth factors in the pericellular matrix

The range of biological outcomes generated by many signalling proteins in development and homeostasis is increased by their interactions with glycosaminoglycans, particularly heparan sulfate (HS). This interaction controls the localization and movement of these signalling proteins, but whether such...

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Detalles Bibliográficos
Autores principales: Sun, Changye, Marcello, Marco, Li, Yong, Mason, David, Lévy, Raphaël, Fernig, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821244/
https://www.ncbi.nlm.nih.gov/pubmed/27009190
http://dx.doi.org/10.1098/rsob.150277