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Evolutionary diversification of retinoic acid receptor ligand-binding pocket structure by molecular tinkering

Whole genome duplications (WGDs) have been classically associated with the origin of evolutionary novelties and the so-called duplication–degeneration–complementation model describes the possible fates of genes after duplication. However, how sequence divergence effectively allows functional changes...

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Detalles Bibliográficos
Autores principales: Gutierrez-Mazariegos, Juliana, Nadendla, Eswar Kumar, Studer, Romain A., Alvarez, Susana, de Lera, Angel R., Kuraku, Shigehiro, Bourguet, William, Schubert, Michael, Laudet, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821253/
https://www.ncbi.nlm.nih.gov/pubmed/27069642
http://dx.doi.org/10.1098/rsos.150484