Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs

Recent evidence has strongly implicated IL‐36 cytokines as key initiators of inflammation in the skin barrier. IL‐36 cytokines belong to the extended IL‐1 family and, similar to most members of this family, are expressed as inactive precursors that require proteolytic processing for activation. Beca...

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Detalles Bibliográficos
Autores principales: Clancy, Danielle M., Henry, Conor M., Davidovich, Pavel B., Sullivan, Graeme P., Belotcerkovskaya, Ekaterina, Martin, Seamus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821354/
https://www.ncbi.nlm.nih.gov/pubmed/27239446
http://dx.doi.org/10.1002/2211-5463.12044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821354/
https://www.ncbi.nlm.nih.gov/pubmed/27239446
http://dx.doi.org/10.1002/2211-5463.12044

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