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Development of ibuprofen-loaded nanostructured lipid carrier-based gels: characterization and investigation of in vitro and in vivo penetration through the skin

An ibuprofen-loaded nanostructured lipid carrier (IBU-NLC) was developed for enhanced skin penetration to improve the treatment of osteoarthritis and other musculoskeletal diseases. The mean particle size was 106 nm, with a spherical morphology, a smooth surface, and a zeta potential of −18.4 mV. X-...

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Detalles Bibliográficos
Autores principales: Sütő, Blanka, Berkó, Szilvia, Kozma, Gábor, Kukovecz, Ákos, Budai-Szűcs, Mária, Erős, Gábor, Kemény, Lajos, Sztojkov-Ivanov, Anita, Gáspár, Róbert, Csányi, Erzsébet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821397/
https://www.ncbi.nlm.nih.gov/pubmed/27099487
http://dx.doi.org/10.2147/IJN.S99198