Unraveling the Deleterious Effects of Cancer-Driven STK11 Mutants Through Conformational Sampling Approach

Tumor suppressor gene, STK11, encodes for serine–threonine kinase, which has a critical role in regulating cell growth and apoptosis. Mutations of the same lead to the inactivation of STK11, which eventually causes different types of cancer. In this study, we focused on identifying those driver muta...

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Detalles Bibliográficos
Autores principales: Lopus, Merlin, Paul, D. Meshach, Rajasekaran, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821432/
https://www.ncbi.nlm.nih.gov/pubmed/27081308
http://dx.doi.org/10.4137/CIN.S38044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821432/
https://www.ncbi.nlm.nih.gov/pubmed/27081308
http://dx.doi.org/10.4137/CIN.S38044

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