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Fabrication of molecular tension probes

A unique bioluminescent imaging probe is introduced for illuminating molecular tension appended by protein–protein interactions (PPIs) of interest. A full-length luciferase is sandwiched between two proteins of interest via minimal flexible linkers. The ligand-activated PPIs append intramolecular te...

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Detalles Bibliográficos
Autores principales: Kim, Sung Bae, Fujii, Rika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821449/
https://www.ncbi.nlm.nih.gov/pubmed/27222821
http://dx.doi.org/10.1016/j.mex.2016.03.008