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CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo

Noncoding RNAs (ncRNAs) comprise an important class of regulatory molecules that mediate a vast array of biological processes. This broad functional capacity has also facilitated the design of artificial ncRNAs with novel functions. To further investigate and harness these capabilities, we developed...

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Detalles Bibliográficos
Autores principales: Shechner, David M., Hacisüleyman, Ezgi, Younger, Scott T., Rinn, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821475/
https://www.ncbi.nlm.nih.gov/pubmed/26030444
http://dx.doi.org/10.1038/nmeth.3433