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CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo
Noncoding RNAs (ncRNAs) comprise an important class of regulatory molecules that mediate a vast array of biological processes. This broad functional capacity has also facilitated the design of artificial ncRNAs with novel functions. To further investigate and harness these capabilities, we developed...
Autores principales: | Shechner, David M., Hacisüleyman, Ezgi, Younger, Scott T., Rinn, John L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821475/ https://www.ncbi.nlm.nih.gov/pubmed/26030444 http://dx.doi.org/10.1038/nmeth.3433 |
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