Enhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction

Parkinson’s disease (PD) is characterized by progressive degeneration of dopaminergic (DA) neurons in the substantial nigra pars compacta. Increasing evidence showed that Wnt/β-catenin pathway and the orphan nuclear receptor Nurr1 play crucial roles in the survival and functional maintenance of DA n...

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Detalles Bibliográficos
Autores principales: Zhang, Limin, Cen, Luan, Qu, Shaogang, Wei, Lei, Mo, Mingshu, Feng, Junmin, Sun, Congcong, Xiao, Yousheng, Luo, Qin, Li, Shaomin, Yang, Xinling, Xu, Pingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821554/
https://www.ncbi.nlm.nih.gov/pubmed/27045591
http://dx.doi.org/10.1371/journal.pone.0152931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821554/
https://www.ncbi.nlm.nih.gov/pubmed/27045591
http://dx.doi.org/10.1371/journal.pone.0152931

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