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High-throughput optical sensing of nucleic acids in a nanopore array

Protein nanopores such as α-hemolysin and MspA can potentially be used to sequence long strands of DNA quickly and at low cost. In order to provide high-speed sequencing, large arrays of nanopores are required that allow the nanopores to individually addressed, but current nanopore sequencing method...

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Detalles Bibliográficos
Autores principales: Huang, Shuo, Romero-Ruiz, Mercedes, Castell, Oliver K., Bayley, Hagan, Wallace, Mark I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821573/
https://www.ncbi.nlm.nih.gov/pubmed/26322943
http://dx.doi.org/10.1038/nnano.2015.189