Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains

Misfolding and aggregation of host proteins are important features of the pathogenesis of neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, frontotemporal dementia and prion diseases. In all these diseases, the misfolded protein increases in amount by a mechanism involvi...

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Detalles Bibliográficos
Autores principales: Carroll, James A., Striebel, James F., Rangel, Alejandra, Woods, Tyson, Phillips, Katie, Peterson, Karin E., Race, Brent, Chesebro, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821575/
https://www.ncbi.nlm.nih.gov/pubmed/27046083
http://dx.doi.org/10.1371/journal.ppat.1005551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821575/
https://www.ncbi.nlm.nih.gov/pubmed/27046083
http://dx.doi.org/10.1371/journal.ppat.1005551

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