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Anti-Apoptotic Effects of Lentiviral Vector Transduction Promote Increased Rituximab Tolerance in Cancerous B-Cells

Diffuse large B-cell lymphoma (DLBCL) is characterized by great genetic and clinical heterogeneity which complicates prognostic prediction and influences treatment efficacy. The most common regimen, R-CHOP, consists of a combination of anthracycline- and immuno-based drugs including Rituximab. It re...

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Detalles Bibliográficos
Autores principales: Ranjbar, Benyamin, Krogh, Louise Bechmann, Laursen, Maria Bach, Primo, Maria Nascimento, Marques, Sara Correia, Dybkær, Karen, Mikkelsen, Jacob Giehm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821607/
https://www.ncbi.nlm.nih.gov/pubmed/27045839
http://dx.doi.org/10.1371/journal.pone.0153069