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Multispecific Organic Cation Transporter 1 (OCT1) from Bos taurus Has High Affinity and Slow Binding Kinetics towards Prostaglandin E2

Organic cation transporter 1 (OCT1, SLC22A1), like many solute carrier 22 (SLC22) family members, is important for the disposition of clinically important drugs, metabolites and signaling molecules. Several studies suggest that SLC22 family (eg. organic anion transporters or OATs and OCTs) bind and...

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Detalles Bibliográficos
Autores principales: He, Xiao, Garza, Denisse, Nigam, Sanjay K., Chang, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821612/
https://www.ncbi.nlm.nih.gov/pubmed/27046168
http://dx.doi.org/10.1371/journal.pone.0152969