Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought

When not engaged in the moment, we often spontaneously represent people, places and events that are not present in the environment. Although this capacity has been linked to the default mode network (DMN), it remains unclear how interactions between the nodes of this network give rise to particular...

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Autores principales: Smallwood, Jonathan, Karapanagiotidis, Theodoros, Ruby, Florence, Medea, Barbara, de Caso, Irene, Konishi, Mahiko, Wang, Hao-Ting, Hallam, Glyn, Margulies, Daniel S., Jefferies, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821638/
https://www.ncbi.nlm.nih.gov/pubmed/27045292
http://dx.doi.org/10.1371/journal.pone.0152272
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author Smallwood, Jonathan
Karapanagiotidis, Theodoros
Ruby, Florence
Medea, Barbara
de Caso, Irene
Konishi, Mahiko
Wang, Hao-Ting
Hallam, Glyn
Margulies, Daniel S.
Jefferies, Elizabeth
author_facet Smallwood, Jonathan
Karapanagiotidis, Theodoros
Ruby, Florence
Medea, Barbara
de Caso, Irene
Konishi, Mahiko
Wang, Hao-Ting
Hallam, Glyn
Margulies, Daniel S.
Jefferies, Elizabeth
author_sort Smallwood, Jonathan
collection PubMed
description When not engaged in the moment, we often spontaneously represent people, places and events that are not present in the environment. Although this capacity has been linked to the default mode network (DMN), it remains unclear how interactions between the nodes of this network give rise to particular mental experiences during spontaneous thought. One hypothesis is that the core of the DMN integrates information from medial and lateral temporal lobe memory systems, which represent different aspects of knowledge. Individual differences in the connectivity between temporal lobe regions and the default mode network core would then predict differences in the content and form of people’s spontaneous thoughts. This study tested this hypothesis by examining the relationship between seed-based functional connectivity and the contents of spontaneous thought recorded in a laboratory study several days later. Variations in connectivity from both medial and lateral temporal lobe regions was associated with different patterns of spontaneous thought and these effects converged on an overlapping region in the posterior cingulate cortex. We propose that the posterior core of the DMN acts as a representational hub that integrates information represented in medial and lateral temporal lobe and this process is important in determining the content and form of spontaneous thought.
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spelling pubmed-48216382016-04-22 Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought Smallwood, Jonathan Karapanagiotidis, Theodoros Ruby, Florence Medea, Barbara de Caso, Irene Konishi, Mahiko Wang, Hao-Ting Hallam, Glyn Margulies, Daniel S. Jefferies, Elizabeth PLoS One Research Article When not engaged in the moment, we often spontaneously represent people, places and events that are not present in the environment. Although this capacity has been linked to the default mode network (DMN), it remains unclear how interactions between the nodes of this network give rise to particular mental experiences during spontaneous thought. One hypothesis is that the core of the DMN integrates information from medial and lateral temporal lobe memory systems, which represent different aspects of knowledge. Individual differences in the connectivity between temporal lobe regions and the default mode network core would then predict differences in the content and form of people’s spontaneous thoughts. This study tested this hypothesis by examining the relationship between seed-based functional connectivity and the contents of spontaneous thought recorded in a laboratory study several days later. Variations in connectivity from both medial and lateral temporal lobe regions was associated with different patterns of spontaneous thought and these effects converged on an overlapping region in the posterior cingulate cortex. We propose that the posterior core of the DMN acts as a representational hub that integrates information represented in medial and lateral temporal lobe and this process is important in determining the content and form of spontaneous thought. Public Library of Science 2016-04-05 /pmc/articles/PMC4821638/ /pubmed/27045292 http://dx.doi.org/10.1371/journal.pone.0152272 Text en © 2016 Smallwood et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Smallwood, Jonathan
Karapanagiotidis, Theodoros
Ruby, Florence
Medea, Barbara
de Caso, Irene
Konishi, Mahiko
Wang, Hao-Ting
Hallam, Glyn
Margulies, Daniel S.
Jefferies, Elizabeth
Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought
title Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought
title_full Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought
title_fullStr Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought
title_full_unstemmed Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought
title_short Representing Representation: Integration between the Temporal Lobe and the Posterior Cingulate Influences the Content and Form of Spontaneous Thought
title_sort representing representation: integration between the temporal lobe and the posterior cingulate influences the content and form of spontaneous thought
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821638/
https://www.ncbi.nlm.nih.gov/pubmed/27045292
http://dx.doi.org/10.1371/journal.pone.0152272
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