Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging

Dietary restriction (DR) improves health, delays tissue aging, and elongates survival in flies and worms. However, studies on laboratory mice and nonhuman primates revealed ambiguous effects of DR on lifespan despite improvements in health parameters. In this study, we analyzed consequences of adult...

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Detalles Bibliográficos
Autores principales: Tang, Duozhuang, Tao, Si, Chen, Zhiyang, Koliesnik, Ievgen Oleksandrovich, Calmes, Philip Gerald, Hoerr, Verena, Han, Bing, Gebert, Nadja, Zörnig, Martin, Löffler, Bettina, Morita, Yohei, Rudolph, Karl Lenhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821645/
https://www.ncbi.nlm.nih.gov/pubmed/26951333
http://dx.doi.org/10.1084/jem.20151100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821645/
https://www.ncbi.nlm.nih.gov/pubmed/26951333
http://dx.doi.org/10.1084/jem.20151100

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