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Arid5a regulates naive CD4(+) T cell fate through selective stabilization of Stat3 mRNA
Balance in signal transducer and activator of transcription (STAT) activation is a key factor in regulating the fate of naive CD4(+) T cells. Here, we demonstrate that AT-rich interactive domain-containing protein 5a (Arid5a) in T cells directs naive CD4(+) T cells to differentiate into inflammatory...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821647/ https://www.ncbi.nlm.nih.gov/pubmed/27022145 http://dx.doi.org/10.1084/jem.20151289 |