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IL-12 drives functional plasticity of human group 2 innate lymphoid cells

Group 2 innate lymphoid cells (ILC2) include IL-5– and IL-13–producing CRTh2(+)CD127(+) cells that are implicated in early protective immunity at mucosal surfaces. Whereas functional plasticity has been demonstrated for both human and mouse ILC3 subsets that can reversibly give rise to IFN-γ–produci...

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Detalles Bibliográficos
Autores principales: Lim, Ai Ing, Menegatti, Silvia, Bustamante, Jacinta, Le Bourhis, Lionel, Allez, Matthieu, Rogge, Lars, Casanova, Jean-Laurent, Yssel, Hans, Di Santo, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821648/
https://www.ncbi.nlm.nih.gov/pubmed/26976630
http://dx.doi.org/10.1084/jem.20151750