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IL-12 drives functional plasticity of human group 2 innate lymphoid cells
Group 2 innate lymphoid cells (ILC2) include IL-5– and IL-13–producing CRTh2(+)CD127(+) cells that are implicated in early protective immunity at mucosal surfaces. Whereas functional plasticity has been demonstrated for both human and mouse ILC3 subsets that can reversibly give rise to IFN-γ–produci...
Autores principales: | Lim, Ai Ing, Menegatti, Silvia, Bustamante, Jacinta, Le Bourhis, Lionel, Allez, Matthieu, Rogge, Lars, Casanova, Jean-Laurent, Yssel, Hans, Di Santo, James P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821648/ https://www.ncbi.nlm.nih.gov/pubmed/26976630 http://dx.doi.org/10.1084/jem.20151750 |
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