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Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design

Traditionally, vaccines have been developed by cultivating infectious agents and isolating the inactivated whole pathogen or some of its purified components. 20 years ago, reverse vaccinology enabled vaccine discovery and design based on information deriving from the sequence of microbial genomes ra...

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Detalles Bibliográficos
Autores principales: Rappuoli, Rino, Bottomley, Matthew J., D’Oro, Ugo, Finco, Oretta, De Gregorio, Ennio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821650/
https://www.ncbi.nlm.nih.gov/pubmed/27022144
http://dx.doi.org/10.1084/jem.20151960