Cargando…

Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design

Traditionally, vaccines have been developed by cultivating infectious agents and isolating the inactivated whole pathogen or some of its purified components. 20 years ago, reverse vaccinology enabled vaccine discovery and design based on information deriving from the sequence of microbial genomes ra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rappuoli, Rino, Bottomley, Matthew J., D’Oro, Ugo, Finco, Oretta, De Gregorio, Ennio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821650/ https://www.ncbi.nlm.nih.gov/pubmed/27022144 http://dx.doi.org/10.1084/jem.20151960

Ejemplares similares

Vaccine Evolution and Its Application to Fight Modern Threats
por: Andreano, Emanuele, et al.
Publicado: (2019)

Editorial: Reverse Vaccinology
por: Moxon, Richard, et al.
Publicado: (2019)

Comparison of Open-Source Reverse Vaccinology Programs for Bacterial Vaccine Antigen Discovery
por: Dalsass, Mattia, et al.
Publicado: (2019)

Designing Vaccines for the Twenty-First Century Society
por: Finco, Oretta, et al.
Publicado: (2014)

Vaccinology in the post−COVID-19 era
por: Rappuoli, Rino, et al.
Publicado: (2021)

Vaccinology – Editorial
por: Pizza, Mariagrazia, et al.
Publicado: (2020)

Bacterial Vaccine Antigen Discovery in the Reverse Vaccinology 2.0 Era: Progress and Challenges
por: Bidmos, Fadil A., et al.
Publicado: (2018)

The respiratory syncytial virus (RSV) prefusion F‐protein functional antibody repertoire in adult healthy donors
por: Andreano, Emanuele, et al.
Publicado: (2021)

Vaccines for the future: learning from human immunology
por: De Gregorio, Ennio, et al.
Publicado: (2012)

Vaccinology at the beginning of the 21st century
por: Wack, Andreas, et al.
Publicado: (2005)

Changing Priorities in Vaccinology: Antibiotic Resistance Moving to the Top
por: Tagliabue, Aldo, et al.
Publicado: (2018)

Dataset of antibody variable region sequence features inferred from a respiratory syncytial virus fusion protein-specific B cell receptor repertoire induced by natural infection of a healthy adult
por: Schneikart, Gerald, et al.
Publicado: (2020)

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens
por: Knudsen, Niels Peter H., et al.
Publicado: (2016)

From empiricism to rational design: a personal perspective of the evolution of vaccine development
por: De Gregorio, Ennio, et al.
Publicado: (2014)

Computational Methods in Immunology and Vaccinology: Design and Development of Antibodies and Immunogens
por: Guarra, Federica, et al.
Publicado: (2023)

Structure-Based Reverse Vaccinology Failed in the Case of HIV Because it Disregarded Accepted Immunological Theory
por: Van Regenmortel, Marc H. V.
Publicado: (2016)

Identification of Streptococcus mitis321A vaccine antigens based on reverse vaccinology
por: Zhang, Qiao, et al.
Publicado: (2018)

Vaccines for the 21st century
por: Delany, Isabel, et al.
Publicado: (2014)

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines
por: Buonsanti, Cecilia, et al.
Publicado: (2016)

NERVE: New Enhanced Reverse Vaccinology Environment
por: Vivona, Sandro, et al.
Publicado: (2006)

Cross-Reactive Bactericidal Antimeningococcal Antibodies Can Be Isolated From Convalescing Invasive Meningococcal Disease Patients Using Reverse Vaccinology 2.0
por: Bidmos, Fadil A., et al.
Publicado: (2018)

Inhibition of T Cell Function During Malaria: Implications for Immunology and Vaccinology
por: Urban, Britta C., et al.
Publicado: (2003)

Antibody avidity, persistence, and response to antigen recall: comparison of vaccine adjuvants
por: Budroni, Sonia, et al.
Publicado: (2021)

Identification of anti-horn fly vaccine antigen candidates using a reverse vaccinology approach
por: Domingues, Luísa N., et al.
Publicado: (2021)

Identification and Evaluation of Novel Antigen Candidates against Salmonella Pullorum Infection Using Reverse Vaccinology
por: Jiang, Zhijie, et al.
Publicado: (2023)

Src Kinases Are Required for a Balanced Production of IL-12/IL-23 in Human Dendritic Cells Activated by Toll-Like Receptor Agonists
por: Kuka, Mirela, et al.
Publicado: (2010)

Vaccine adjuvant MF59 promotes the intranodal differentiation of antigen-loaded and activated monocyte-derived dendritic cells
por: Cioncada, Rossella, et al.
Publicado: (2017)

Reverse Vaccinology: An Approach for Identifying Leptospiral Vaccine Candidates
por: Dellagostin, Odir A., et al.
Publicado: (2017)

African Swine Fever Vaccinology: The Biological Challenges from Immunological Perspectives
por: Zhu, James J.
Publicado: (2022)

Identification by Reverse Vaccinology of Three Virulence Factors in Burkholderia cenocepacia That May Represent Ideal Vaccine Antigens
por: Irudal, Samuele, et al.
Publicado: (2023)

Self-assembling protein nanoparticles in the design of vaccines
por: López-Sagaseta, Jacinto, et al.
Publicado: (2015)

COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning
por: Ong, Edison, et al.
Publicado: (2020)

COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning
por: Ong, Edison, et al.
Publicado: (2020)

Designing of a Novel Multi-Antigenic Epitope-Based Vaccine against E. hormaechei: An Intergraded Reverse Vaccinology and Immunoinformatics Approach
por: Albekairi, Thamer H., et al.
Publicado: (2022)

Genome-Based Multi-Antigenic Epitopes Vaccine Construct Designing against Staphylococcus hominis Using Reverse Vaccinology and Biophysical Approaches
por: Nawaz, Mahreen, et al.
Publicado: (2022)

Vaccines for the twenty-first century society
por: Rappuoli, Rino, et al.
Publicado: (2011)

Identification of Mycobacterium tuberculosis Antigens with Vaccine Potential Using a Machine Learning-Based Reverse Vaccinology Approach
por: Teahan, Blaine, et al.
Publicado: (2021)

The Screening of the Protective Antigens of Aeromonas hydrophila Using the Reverse Vaccinology Approach: Potential Candidates for Subunit Vaccine Development
por: Zhang, Ting, et al.
Publicado: (2023)

Enhancing the Biological Relevance of Machine Learning Classifiers for Reverse Vaccinology
por: Heinson, Ashley I., et al.
Publicado: (2017)

Antibiotic Resistance Determinant-Focused Acinetobacter baumannii Vaccine Designed Using Reverse Vaccinology
por: Ni, Zhaohui, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_33a52dmmv1ep2rki72nojsht85