Cargando…

HSF-1 activates the ubiquitin proteasome system to promote non-apoptotic developmental cell death in C. elegans

Apoptosis is a prominent metazoan cell death form. Yet, mutations in apoptosis regulators cause only minor defects in vertebrate development, suggesting that another developmental cell death mechanism exists. While some non-apoptotic programs have been molecularly characterized, none appear to contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinet, Maxime J, Malin, Jennifer A, Abraham, Mary C, Blum, Elyse S, Silverman, Melanie R, Lu, Yun, Shaham, Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821803/
https://www.ncbi.nlm.nih.gov/pubmed/26952214
http://dx.doi.org/10.7554/eLife.12821