Oxidative Pentose Phosphate Pathway Inhibition Is A Key Determinant of Antimalarial Induced Cancer Cell Death

Despite immense interest in employing antimalarials as autophagy inhibitors to treat cancer, it remains unclear if these agents act predominantly via autophagy inhibition or whether other pathways direct their anti-cancer properties. By comparing the treatment effects of the antimalarials chloroquin...

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Detalles Bibliográficos
Autores principales: Salas, Eduardo, Roy, Srirupa, Marsh, Timothy, Rubin, Brian, Debnath, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821829/
https://www.ncbi.nlm.nih.gov/pubmed/26434592
http://dx.doi.org/10.1038/onc.2015.348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821829/
https://www.ncbi.nlm.nih.gov/pubmed/26434592
http://dx.doi.org/10.1038/onc.2015.348

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