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Oxidative Pentose Phosphate Pathway Inhibition Is A Key Determinant of Antimalarial Induced Cancer Cell Death
Despite immense interest in employing antimalarials as autophagy inhibitors to treat cancer, it remains unclear if these agents act predominantly via autophagy inhibition or whether other pathways direct their anti-cancer properties. By comparing the treatment effects of the antimalarials chloroquin...
Autores principales: | Salas, Eduardo, Roy, Srirupa, Marsh, Timothy, Rubin, Brian, Debnath, Jayanta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821829/ https://www.ncbi.nlm.nih.gov/pubmed/26434592 http://dx.doi.org/10.1038/onc.2015.348 |
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