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Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis

Accessory sigma factors, which reprogram RNA polymerase to transcribe specific gene sets, activate bacterial adaptive responses to noxious environments. Here we reconstruct the complete sigma factor regulatory network of the human pathogen Mycobacterium tuberculosis by an integrated approach. The ap...

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Detalles Bibliográficos
Autores principales: Chauhan, Rinki, Ravi, Janani, Datta, Pratik, Chen, Tianlong, Schnappinger, Dirk, Bassler, Kevin E., Balázsi, Gábor, Gennaro, Maria Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821874/
https://www.ncbi.nlm.nih.gov/pubmed/27029515
http://dx.doi.org/10.1038/ncomms11062