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Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis
Accessory sigma factors, which reprogram RNA polymerase to transcribe specific gene sets, activate bacterial adaptive responses to noxious environments. Here we reconstruct the complete sigma factor regulatory network of the human pathogen Mycobacterium tuberculosis by an integrated approach. The ap...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821874/ https://www.ncbi.nlm.nih.gov/pubmed/27029515 http://dx.doi.org/10.1038/ncomms11062 |