Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

During the process of reprogramming to induced pluripotent stem (iPS) cells, somatic cells switch from oxidative to glycolytic metabolism, a transition associated with profound mitochondrial reorganization. Neither the importance of mitochondrial remodelling for cell reprogramming, nor the molecular...

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Detalles Bibliográficos
Autores principales: Prieto, Javier, León, Marian, Ponsoda, Xavier, Sendra, Ramón, Bort, Roque, Ferrer-Lorente, Raquel, Raya, Angel, López-García, Carlos, Torres, Josema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821885/
https://www.ncbi.nlm.nih.gov/pubmed/27030341
http://dx.doi.org/10.1038/ncomms11124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821885/
https://www.ncbi.nlm.nih.gov/pubmed/27030341
http://dx.doi.org/10.1038/ncomms11124

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