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Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

During the process of reprogramming to induced pluripotent stem (iPS) cells, somatic cells switch from oxidative to glycolytic metabolism, a transition associated with profound mitochondrial reorganization. Neither the importance of mitochondrial remodelling for cell reprogramming, nor the molecular...

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Detalles Bibliográficos
Autores principales:	Prieto, Javier, León, Marian, Ponsoda, Xavier, Sendra, Ramón, Bort, Roque, Ferrer-Lorente, Raquel, Raya, Angel, López-García, Carlos, Torres, Josema
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821885/ https://www.ncbi.nlm.nih.gov/pubmed/27030341 http://dx.doi.org/10.1038/ncomms11124

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